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1

Genetic risk factors associated with lipid-lowering drug-induced myopathies

Georgirene D. Vladutiu, Zachary Simmons, Paul J. Isackson, Mark Tarnopolsky, Wendy L. Peltier, Alexandru C. Barboi, Naganand Sripathi, Robert L. Wortmann, Paul S. Phillips

Journal:

Year:

2006

Language:

english

File:

PDF, 113 KB

english, 2006

2

Association of common variants in the human eyes shut ortholog (EYS) with statin-induced myopathy: Evidence for additional functions of EYS

Paul J. Isackson, Heather M. Ochs-Balcom, Changxing Ma, John B. Harley, Wendy Peltier, Mark Tarnopolsky, Naganand Sripathi, Robert L. Wortmann, Zachary Simmons, Jon D. Wilson, Stephen A. Smith, Alexan

Journal:

Year:

2011

Language:

english

File:

PDF, 341 KB

english, 2011

3

Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus

Heather S. Oliff, Nicole C. Berchtold, Paul Isackson, Carl W. Cotman

Journal:

Molecular Brain Research

Year:

1998

Language:

english

File:

PDF, 215 KB

english, 1998

4

Novel mutations in the gene encoding very long-chain acyl-CoA dehydrogenase identified in patients with partial carnitine palmitoyltransferase ii deficiency

Isackson, Paul J., Sutton, Kristin A., Hostetler, Karl Y., Vladutiu, Georgirene D.

Journal:

Year:

2013

Language:

english

File:

PDF, 398 KB

english, 2013

5

Acidic fibroblast growth factor mRNA is expressed by basal forebrain and striatal cholinergic neurons

Bizon, Jennifer L., Lauterborn, Julie C., Isackson, Paul J., Gall, Christine M.

Journal:

The Journal of Comparative Neurology

Year:

1996

Language:

english

File:

PDF, 1.52 MB

english, 1996

6

Cell-specific expression of type II calcium/calmodulin-dependent protein kinase isoforms and glutamate receptors in normal and visually deprived lateral geniculate nucleus of monkeys

Tighilet, Brahim, Huntsman, Molly M., Hashikawa, Tsutomu, Murray, Karl D., Isackson, Paul J., Jones, Edward G.

Journal:

The Journal of Comparative Neurology

Year:

1998

Language:

english

File:

PDF, 1.92 MB

english, 1998

7

Altered mRNA expression for brain-derived neurotrophic factor and type II calcium/Calmodulin-dependent protein kinase in the hippocampus of patients with intractable temporal lobe epilepsy

Murray, Karl D., Isackson, Paul J., Eskin, Thomas A., King, Michael A., Montesinos, Sylvia P., Abraham, Linda A., Roper, Steven N.

Journal:

The Journal of Comparative Neurology

Year:

2000

Language:

english

File:

PDF, 893 KB

english, 2000

8

Preferential expression of myelencephalon-specific protease by oligodendrocytes of the adult rat spinal cord white matter

Isobel A. Scarisbrick, Kuniko Asakura, Sachiko Blaber, Michael Blaber, Paul J. Isackson, Tom Bieto, Moses Rodriguez, Anthony J. Windebank

Journal:

Year:

2000

Language:

english

File:

PDF, 611 KB

english, 2000

9

MSP, a trypsin-like serine protease, is abundantly expressed in the human nervous system

Isobel A. Scarisbrick, Paul J. Isackson, Bogoljub Ciric, Anthony J. Windebank, Moses Rodriguez

Journal:

The Journal of Comparative Neurology

Year:

2001

Language:

english

File:

PDF, 1.09 MB

english, 2001

10

Nerve growth factor mRNA-containing cells are distributed within regions of cholinergic neurons in the rat basal forebrain

Julie C. Lauterborn, Paul J. Isackson, Christine M. Gall

Journal:

The Journal of Comparative Neurology

Year:

1991

Language:

english

File:

PDF, 1.04 MB

english, 1991

11

Dopaminergic neurons in rat ventral midbrain express brain-derived neurotrophic factor and neurotrophin-3 mRNAs

Kim B. Seroogy, Kerstin H. Lundgren, Tien M. D. Tran, Kathleen M. Guthrie, Paul J. Isackson, Christine M. Gall

Journal:

The Journal of Comparative Neurology

Year:

1994

Language:

english

File:

PDF, 2.08 MB

english, 1994

12

Role of glandular kallikreins as growth factor processing enzymes: Structural and evolutionary considerations

Paul J. Isackson, Joan C. Dunbar, Ralph A. Bradshaw

Journal:

Journal of Cellular Biochemistry

Year:

1987

Language:

english

File:

PDF, 715 KB

english, 1987

13

Two-dimensional gel electrophoresis of nonhistone chromatin proteins with nonequilibrium pH gradient electrophoresis as the first dimension

Dana Tyrell, Paul J. Isackson, Gerald R. Reeck

Journal:

Analytical Biochemistry

Year:

1982

Language:

english

File:

PDF, 3.42 MB

english, 1982

14

Ionic interactions between proteins in nonequilibrium pH gradient electrophoresis: Histones affect the migration of high mobility group nonhistone chromatin proteins

Lisa Wen, Rodney K. Tweten, Paul J. Isackson, John J. Iandolo, Gerald R. Reeck

Journal:

Analytical Biochemistry

Year:

1983

Language:

english

File:

PDF, 7.53 MB

english, 1983

15

Attenuation of the seizure-induced expression of BDNF mRNA in adult rat brain by an inhibitor of calcium/calmodulin-dependent protein kinases

Karl D. Murray, Valerie Y. Hayes, Christine M. Gall, Paul J. Isackson

Journal:

European Journal of Neuroscience

Year:

1998

Language:

english

File:

PDF, 704 KB

english, 1998

16

Synthetic chimeras of mouse growth factor-associated glandular kallikreins. II. Growth factor binding properties

Michael Blaber, Paul J. Isackson, Ralph A. Bradshaw, Hazel M. Holden

Journal:

Protein Science

Year:

1993

Language:

english

File:

PDF, 4.46 MB

english, 1993

17

Synthetic chimeras of mouse growth factor-associated glandular kallikreins. I. Kinetic properties

Michael Blaber, Paul J. Isackson, Ralph A. Bradshaw, John P. Burnier, James C. Marsters Jr.

Journal:

Protein Science

Year:

1993

Language:

english

File:

PDF, 1.60 MB

english, 1993

18

The characterization of recombinant mouse glandular kallikreins from E. coli

Michael Blaber, Paul J. Isackson, Ralph. A. Bradshaw

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1990

Language:

english

File:

PDF, 1.05 MB

english, 1990

19

Expression of the alpha subunit of 7S nerve growth factor in the mouse submandibular gland

Paul J. Isackson, Steven J. Nisco, Ralph A. Bradshaw

Journal:

Neurochemical Research

Year:

1987

Language:

english

File:

PDF, 1.08 MB

english, 1987

20

Isolation and Sequence of a cDNA Clone of β-Nerve Growth Factor from the Guinea Pig Prostate Gland

Martin A. Schwarz, Douglas Fisher, Ralph A. Bradshaw, Paul J. Isackson

Journal:

Journal of Neurochemistry

Year:

1989

Language:

english

File:

PDF, 770 KB

english, 1989

21

Inhibitors of Urokinase and Thrombin in Cultured Neural Cells

Steven L. Wagner, Alice L. Lau, Ann Nguyen, Jun Mimuro, David J. Loskutoff, Paul J. Isackson, Dennis D. Cunningham

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 1.20 MB

english, 1991

22

Haloperidol but Not Clozapine Increases Neurotensin Receptor mRNA Levels in Rat Substantia Nigra

Carolyn Bolden-Watson, Michael A. Watson, Karl D. Murray, Paul J. Isackson, Elliott Richelson

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 706 KB

english, 1993

23

Domain structure in high molecular weight high mobility group nonhistone chromatin proteins

Reeck, Gerald R., Isackson, Paul J., Teller, David C.

Journal:

Year:

1982

File:

PDF, 378 KB

1982

24

Production of HMG-3 by limited trypsin digestion of purified high-mobility-group nonhistone chromatin proteins

Paul J. Isackson, Jacqueline Beaudoin, Mark A. Hermodson, Gerald R. Reeck

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1983

Language:

english

File:

PDF, 1.17 MB

english, 1983

25

Seizure-Induced Increases in NGF mRNA Exhibit Different Time Courses across Forebrain Regions and Are Biphasic in Hippocampus

Julie C. Lauterborn, Paul J. Isackson, Christine M. Gall

Journal:

Experimental Neurology

Year:

1994

File:

PDF, 3.04 MB

1994

26

Induction of nerve growth factor and basic fibroblast growth factor mRNA following clenbuterol: Contrasting anatomical and cellular localization

Valerie Y. Hayes, Paul J. Isackson, Michele Fabrazzo, Paolo Follesa, Italo Mocchetti

Journal:

Experimental Neurology

Year:

1995

Language:

english

File:

PDF, 21.86 MB

english, 1995

27

Isolation and separation of chicken erythrocyte high mobility group non-histone chromatin proteins by chromatography on phosphocellulose

Paul J. Isackson, William A. Debold, Gerald R. Reeck

Journal:

Year:

1980

Language:

english

File:

PDF, 890 KB

english, 1980

28

Comparison of the salt dissociations of high molecular weight HMG non-histone chromatin proteins from double-stranded DNA and from chromatin

Paul J. Isackson, Leonard G. Clow, Gerald R. Reeck

Journal:

Year:

1981

Language:

english

File:

PDF, 588 KB

english, 1981

29

Comparison of mammalian, chicken and Xenopus brain-derived neurotrophic factor coding sequences

Paul J. Isackson, Melvin D. Towner, Molly M. Huntsman

Journal:

Year:

1991

Language:

english

File:

PDF, 578 KB

english, 1991

30

Trophic factor response to neuronal stimuli or injury

Paul J Isackson

Journal:

Current Opinion in Neurobiology

Year:

1995

Language:

english

File:

PDF, 827 KB

english, 1995

31

Myoadenylate deaminase deficiency caused by alternative splicing due to a novel intronic mutation in the AMPD1 gene

Paul J. Isackson, Heather Bujnicki, Cary O. Harding, Georgirene D. Vladutiu

Journal:

Molecular Genetics and Metabolism

Year:

2005

Language:

english

File:

PDF, 255 KB

english, 2005

32

A novel mutation in the PYGM gene in a family with pseudo-dominant transmission of McArdle disease

Paul J. Isackson, Mark Tarnopolsky, Georgirene D. Vladutiu

Journal:

Molecular Genetics and Metabolism

Year:

2005

Language:

english

File:

PDF, 410 KB

english, 2005

33

Identification of 16 new disease-causing mutations in the CPT2 gene resulting in carnitine palmitoyltransferase II deficiency

Paul J. Isackson, Michael J. Bennett, Georgirene D. Vladutiu

Journal:

Molecular Genetics and Metabolism

Year:

2006

Language:

english

File:

PDF, 1.61 MB

english, 2006

34

CPT2 gene mutations resulting in lethal neonatal or severe infantile carnitine palmitoyltransferase II deficiency

Paul J. Isackson, Michael J. Bennett, Uta Lichter-Konecki, Mary Willis, William L. Nyhan, V. Reid Sutton, Ingrid Tein, Georgirene D. Vladutiu

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 524 KB

english, 2008

35

Genetic risk for malignant hyperthermia in non-anesthesia-induced myopathies

Georgirene D. Vladutiu, Paul J. Isackson, Kenneth Kaufman, John B. Harley, Beth Cobb, Lisa Christopher-Stine, Robert L. Wortmann

Journal:

Molecular Genetics and Metabolism

Year:

2011

Language:

english

File:

PDF, 208 KB

english, 2011

36

Organization, sequence and functional analysis of a mouse BDNF promoter

Valerie Y Hayes, Melvin D Towner, Paul J Isackson

Journal:

Molecular Brain Research

Year:

1997

Language:

english

File:

PDF, 426 KB

english, 1997

37

Transcript-specific effects of adrenalectomy on seizure-induced BDNF expression in rat hippocampus

Julie C Lauterborn, Frantz R Poulsen, Curtiss T Stinis, Paul J Isackson, Christine M Gall

Journal:

Molecular Brain Research

Year:

1998

Language:

english

File:

PDF, 607 KB

english, 1998

38

Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript

Nicole C Berchtold, Heather S Oliff, Paul Isackson, Carl W Cotman

Journal:

Molecular Brain Research

Year:

1999

Language:

english

File:

PDF, 780 KB

english, 1999

39

Removal of degradation products from calf thymus high mobility group non-histone chromatin proteins by chromatography on immobilized double-stranded DNA

Paul J. Isackson, Gerald R. Reeck

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1982

Language:

english

File:

PDF, 322 KB

english, 1982

40

BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: Temporal patterns of induction distinct from NGF

Isackson, Paul J., Huntsman, Molly M., Murray, Karl D., Gall, Christine M.

Journal:

Year:

1991

Language:

english

File:

PDF, 12.89 MB

english, 1991

41

In situ hybridization localization of choline acetyltransferase mRNA in adult rat brain and spinal cord

Lauterborn, Julie C., Isackson, Paul J., Montalvo, Raul, Gall, Christine M.

Journal:

Molecular Brain Research

Year:

1993

Language:

english

File:

PDF, 2.41 MB

english, 1993

42

Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus

Gall, Christine, Murray, Karl, Isackson, Paul J.

Journal:

Molecular Brain Research

Year:

1991

Language:

english

File:

PDF, 5.56 MB

english, 1991

43

Seizures increase basic fibroblast growth factor mRNA in adult rat forebrain neurons and glia

Gall, Christine M., Berschauer, Robert, Isackson, Paul J.

Journal:

Molecular Brain Research

Year:

1994

Language:

english

File:

PDF, 2.56 MB

english, 1994

44

Identification of a Polymorphism in the Human Neurotensin Receptor Gene

WATSON, MICHAEL, ISACKSON, PAUL J., MAKKER, MANISHA, YAMADA, MITSUHIKO S., YAMADA, MISA, CUSACK, BERNADETTE, RICHELSON, ELLIOTT

Journal:

Mayo Clinic Proceedings

Year:

1993

Language:

english

File:

PDF, 714 KB

english, 1993

45

In situ hybridization reveals VIP precursor mRNA-containing neurons in monkey and rat neocortex

Benson, Deanna L., Isackson, Paul J., Jones, Edward G.

Journal:

Molecular Brain Research

Year:

1991

Language:

english

File:

PDF, 3.97 MB

english, 1991

46

Brain-derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons

Gall, Christine M., Gold, Stephen J., Isackson, Paul J., Seroogy, Kim B.

Journal:

Molecular and Cellular Neuroscience

Year:

1992

Language:

english

File:

PDF, 8.99 MB

english, 1992

47

Dominant Negative Mutations in the Tn10 tet Repressor: Evidence for Use of the Conserved Helix-Turn-Helix Motif in DNA Binding

Paul J. Isackson and Kevin P. Bertrand

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 1.50 MB

english, 1985

48

Protease Nexin-1, an Antithrombin with Neurite Outgrowth Activity, is Reduced in Alzheimer Disease

Steven L. Wagner, James W. Geddes, Carl W. Cotman, Alice L. Lau, David Gurwitz, Paul J. Isackson and Dennis D. Cunningham

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.09 MB

english, 1989

49

Mouse 7S nerve growth factor: complete sequence of a cDNA coding for the .alpha.-subunit precursor and its relationship to serine proteases

Isackson, Paul J., Ullrich, Axel, Bradshaw, Ralph A.

Journal:

Year:

1984

Language:

english

File:

PDF, 685 KB

english, 1984

50

High mobility group chromosomal proteins isolated from nuclei and cytosol of cultured hepatoma cells are similar

Isackson, Paul J., Bidney, Dennis L., Reeck, Gerald R., Neihart, Natasha K., Bustin, Michael

Journal:

Year:

1980

Language:

english

File:

PDF, 3.20 MB

english, 1980

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